What is the best age for hip replacement?

A July 2022 study (1) examined the research on what is the best age for a total hip replacement. In some studies the researchers found that “age has shown no effect on outcome in some evaluations, while others have reported higher functional improvement in younger patients.” The aim then of their study was to determine if outcome after total hip replacement varies based on patient age.

  • Prior to surgery, younger patients (less than 55 years) reported worse pain, function, and quality of life than other three patient groups.
    • 55-64 years [older adult],
    • 65-74 years [early elder],
    • and more than 75 years [late elder])
  • At one year after total hip replacement, younger patients ( less than 55 years) reported slightly worse pain and quality of life but better function scores than the three older patients’ groups.
  • Younger patients (less than 55 years) achieved higher baseline to one year pain, and function score changes when compared to the older patients’ groups.
  • The quality of life score changes was not different among the four age groups.
  • Conclusion: “Although there are statistically significant differences in pain relief, functional improvement, and quality of life between younger and older patients among different patients’ age groups, there is no clinically significant difference. Total hip replacement provides an improvement in quality of life by decreasing pain and increasing function in all four age groups, with large improvements in Patient-Reported Outcome Measures scores without clinically significant age-related differences in Total hip replacement outcome at 1 year.”

A July 2022 study (2) examined the concern of the survivorship of a total hip replacement in younger patients. The primary concern is the subsequent need for revision surgery in later life. This stuyd included 2,461 patients (2,814 hips) with minimum 2-year follow-up who underwent primary total hip replacement.  There were 561 patients (643 total hip replacement; 23%) aged 55 or younger and 1,900 (2,171 total hip replacement; 77%) older than 55.

The researchers follow-up was 5 years for both groups. There were more male patients in the younger (55%) than older (41%) group. Body mass index (BMI) was higher in younger patients independent of gender. Kaplan-Meier survival to endpoint of all cause revision was similar between groups at 12 years with 97.5% for younger versus 97.1% for older patients. Most frequent reason for revision overall was periprosthetic femoral fracture univariate analysis revealed risk factors were female gender and age being more than 65 years old.

The researchers concluded that “Use of modern polyethylene, such as vitamin E-stabilized highly cross-linked, liners during total hip replacement may improve survivorship in younger patients undergoing total hip replacement.”

A July 2022 study (3) looked to see what factors could increase the longevity of a total hip replacement. The researchers focused on highly cross-linked polyethylene (a polyethylene designed in the 1990’s to offset wear and tear of the hardware components). They note that since its introduction, studies on the longevity of this polyethylene are lacking.

The researchers evaluated patients who underwent total hip arthroplasty with highly cross-linked polyethylene at an average 10-year follow-up for (1) linear and volumetric wear rates, (2) patient and implant characteristics, (3) implant survivorships, and (4) functional scores. The general findings were:

  • Younger age patients had higher volumetric wear of the polyethylene.
  • Increasing body mass index trended toward higher total and yearly linear and volumetric wear.
  • Ten (of the total 110) patients (in the study) required revisions
  • Younger age and higher body mass index at the time of surgery may be important patient characteristics influencing long-term wear.

Return to sports prompts younger patients to get hip replacement

A March 2021 study (4) examined the impact of total hip replacements in patient under the age of 50. The authors note that “an increasing number of younger (less than 50 years old) and active patients will receive surgical interventions, and expectations for an active lifestyle will accordingly increase. In addition, surgeons now have a growing array of techniques and implant materials to choose from. Despite these developments, evidence to provide the best standard-of-care to patients with high expectations for return to sports (RTS) is scarce and urgently needed.”

The researchers of this study offered findings based what recommendations arthroplasty surgeons currently make to patients with high return to sports expectations, what factors may influence their recommendations and what surgical techniques and implant specifications are considered favorable in the treatment of patients with a more active lifestyle?

  • “The majority of surgeons (81.9%) were in favor of return to sports after total hip replacements. Risks associated with sports after total hip replacements were considered minimal (1%), with periprosthetic fractures ranking highest, followed by hip dislocation and polyethylene wear. Some surgical decision-making was influenced by high-return to sports expectations in regard to implant fixation, stem type, femoral head diameter, and bearing-surface tribology. We observed an increasingly liberal counseling of patients for high-impact sports.”

1 Ayers DC, Yousef M, Zheng H, Yang W, Franklin PD. Do Patient Outcomes Vary by Patient Age Following Primary Total Hip Arthroplasty?. The Journal of Arthroplasty. 2022 Mar 12.
2 Lombardi Jr AV, Byrd ZO, Berend KR, Morris MJ, Adams JB, Crawford DA. Mid-Term Survival of Total Hip Arthroplasty in Patients Younger Than 55-year-old. The Journal of Arthroplasty. 2022 Feb 28.
3 Sax OC, Douglas SJ, Chen Z, Mont MA, Nace J, Delanois RE. Low Wear at 10-Year Follow-Up of a Second-Generation Highly Cross-Linked Polyethylene in Total Hip Arthroplasty. The Journal of Arthroplasty. 2022 Feb 22.
4 Vu-Han T, Hardt S, Ascherl R, Gwinner C, Perka C. Recommendations for return to sports after total hip arthroplasty are becoming less restrictive as implants improve. Archives of orthopaedic and trauma surgery. 2021 Mar;141(3):497-507.

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